We have recently shown that cancer‐derived exosomes modulate the crosstalk between leukaemia cells and the bone marrow microenvironment; in particular, we have reported that CML cells release exosomes and that the addition of these vesicles to vascular endothelial cells as well as to bone marrow stromal cells affects both in vitro and in vivo tumour progression, through the stimulation of an interleukin 8‐mediated paracrine and autocrine loops 10, 11, 12, 13. Here, CXCL8 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.