RHOA, a downstream component of non-canonical Wnt signalling and FZD7 [179], is upregulated in GC [174,180], whilst ROR1, a tyrosine kinase like receptor able to transmit non-canonical Wnt5a signals [181], is phosphorylated in HS746T human gastric cancer cells, via a Met dependant mechanism [31]. The gene discussed is FZD7; the disease is gastric cancer.