In 2006, Morgan et al. [4] and Khateeb et al. [5] have independently shown that mutations in PLA2G6 (phospholipase A2 Group 6), encoding a calcium-independent group VIA phospholipase A2 enzyme (iPLA2-VIA), cause INAD and ANAD. The gene discussed is PLA2G6; the disease is neurodegeneration with brain iron accumulation 2A.