Five studies3,5,18,20,22 described side effects after treatment with vincristine including neuropathy (n = 3), abdominal pain (n = 3), hemorrhagic cystitis (n = 1), constipation (n = 1), loss of appetite (n = 2), and elevations of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels (n = 2) (Table 2). This evidence concerns the gene GPT and neuropathy.