Since CBZ-induced SJS and TEN occur by a direct pharmacological interaction between carbamazepine and the HLA-B*15:02 molecule which activates particular types of T cell receptors [11,12], clinicains should be aware of the association between HLA-B*15:02 and CBZ-induced SJS and TEN in any Asian population whose HLA-B*15:02 frequency is high. Here, HLA-B is linked to toxic epidermal necrolysis.