DNAH8 and systemic lupus erythematosus: It has recently been shown that the specific reorganization of the immune system during spontaneous development of a profound SLE-like pathology in MRL-lpr/lpr mice [49–51] and MS-like pathology in experimental autoimmune encephalomyelitis mice [31] is associated with changes in the differentiation profile, the level of proliferation of bone marrow hematopoietic stem cells and the production of DNase, protease, ATPase, and amylase abzymes.