Eight genes (ACSM1, TDRD1, PLA2G7, SPON2, DLX1, CACNA1D, RHOU, and LMNB1) were selected by bioinformatics data mining, based on their overexpression in primary PCa compared to normal tissue samples mainly in the MSKCC data set; and expression was confirmed in other data sets such as the IST database. Here, SPON2 is linked to posterior cortical atrophy.