KLF2 and non-small cell lung carcinoma: In our previous study, we have reported that KLF2 expression is downregulated in NSCLC tissues and cells, and its overexpression inhibited migration and proliferation of NSCLC cells.23 Here, we performed gain-of-function assays of LATS2 in H1299 cells, and the western blot assays showed that LATS2 expression was significantly increased in H1299 cells that were transfected with pCDNA-LATS2 compared with control cells (Figure 6a).