Kriopoulos et al. and Gabhale et al. reported that pleural CRP levels provided excellent sensitivity (100%) and good specificity (79, 98.8%) at cut-off levels of 5.3 and 9.08 mg/dL, respectively, for differentiating between parapneumonic effusion and tuberculosis or malignant effusions [2, 18]. This evidence concerns the gene CRP and tuberculosis.