Intranasal challenge with saline/OVA did not induce allergic airway inflammation, however the SNP/OVA-treated groups showed significant airway inflammation, remarkable AHR, increased inflammatory cell counts in the BALF, perivascular/peribronchial inflammation in histopathology, and increased levels of various cytokines compared to the saline/OVA-treated group. This evidence concerns the gene AHR and inflammation.