ALB and systemic lupus erythematosus: However, serum chloride (p = 0.004), albumin (p = 0.002), aspartate aminotransferase (AST) levels (p = 0.004) and SLE disease activity index (SLEDAI) (p = 0.026) were significantly higher and serum calcium levels (p = 0.004) were significantly lower in SLE patients with hyponatremia than those without.