In univariate analyses, there were no significant differences in WBC counts and SLEDAI between the two groups (p > 0.05) and ESR (p = 0.053) and CRP levels (p = 0.053) were higher in SLE patients with hyponatremia (n = 18) than those without (n = 140) with borderline significances (Supplementary Table S4). This evidence concerns the gene CRP and systemic lupus erythematosus.