No such effect was observed in the FGFR4−/FGF19+ MDA-MB-231 cells or in the FGFR−/FGF19− MCF-10A cells, suggesting that only cancer cells that co-expressed FGFR4 and FGF19 might be susceptible to FGFR4/FGF19 inhibition. The gene discussed is FGFR4; the disease is cancer.