An additional HLA-A2–restricted T-cell line, specific for brachyury peptide, was derived from another prostate cancer patient; after stimulation with epacadostat (1 μM)– treated DCs, the lysis of the human breast cancer cell line MDA-MB231 increased from 3.5% to 26.9% (Table 3C). Here, TBX1 is linked to Familial prostate cancer.