WDR5 significantly binds to promoter region of Tyrosine-protein kinase Lyn (Lyn), B-cell CLL/lymphoma 9 (BCL9), Ras-related protein Rab-28 (RAb28), Cluster of Differentiation 93 (CD93), Mediater complex subunit 24 (MED24) and RBM22 in Nalm6 B-ALL cells (Figure 4B) and U937 AML cells (Figure 4C). Here, LYN is linked to acute myeloid leukemia.