In future studies of young lung cancer and its association with the EGFR mutation, additional factors should be included in the analysis, such as family lung cancer history, smoking index, age of starting smoking, passive smoking, `environmental exposures, and status of other driver oncogene, including ALK rearrangement, BRAF, KRAS, ROS-1 and HER-2. The gene discussed is ERBB2; the disease is lung cancer.