While the presence of other CC chemokines including CCL3, CCL4, CCL18 and CCL22 and some CXC chemokines, in particular CXCL8 [46], has been correlated with the presence of macrophages, it still remains to be determined whether they play a role in the recruitment or in the maintenance of the TAM in tumor tissue [47]. Here, CCL22 is linked to neoplasm.