A list of genes that showed 3-fold upregulation, including NNAT, CHCHD2, PTGR1, and NLRP2, or downregulation, such as IFITM1, IL13RA2, BGN, and NKX2-2 in PD patient-derived lines relative to healthy control is shown in Table 3. The gene discussed is PTGR1; the disease is Parkinson disease.