After neutron irradiation, the MST of mice with CD133 + SU2 glioma xenografts exposed to PD-CD133/BSH in combination with BSH was 61.8 ± 11.4 days, compared with 46.7 ± 9.4 days in mice implanted with CD133- SU2 glioma xenografts: 45.9 ± 9.1 days with BSH alone, and 35.8 ± 4.6 days with PD-CD133/BSH alone. This evidence concerns the gene PROM1 and central nervous system cancer.