Of these most common proteins, there are over 25 published cancer-associated antigens, including at least 12 proteins that are among the NCI’s list of prioritized cancer antigens [8] such as TP53, survivin, EphA2, cyclin B1, XAGE1, Her2/neu, RhoC, Mesothelin, Legumain, PDGFRb, FOSL1 and KRAS [9]. The gene discussed is TP53; the disease is cancer.