These findings indicated that MUC1 positive might be related to invasiveness of gastric carcinoma cells, which is in accordance with the experimental results that MUC1 positive tumors were associated with synchronous liver metastasis and overexpression of MUC1 in carcinoma cells decreases cell-cell interaction and increases the metastatic capacity of carcinoma cells, favoring invasion of tumor cells into the underlying stroma, lymph, and blood vessels [36]. Here, MUC1 is linked to metastasis.