To examine if cervical cancers arising in Bi-L E7/K14-tTA mice on the FancD2-deficient background remain dependent upon continued expression of E7, we likewise administered doxycycline to Bi-L E7/K14-tTA/FancD2−/− mice for the last month on estrogen to repress E7 expression. Here, FANCD2 is linked to cervical carcinoma.