OxP: oxidative phosphorylation; CML: chronic myeloid leukaemia; Ins: insulin signalling pathway; Cancer: pathways in cancer; p53: p53 signalling pathway; Ad junc: adherens junction; HCM: hypertrophic cardiomyopathy; ARVC: arrhythmogenic right ventricular cardiomyopathy; Melano: melanogenesis; Endo: endocytosis; Hedge: Hedgehog signalling pathway. The gene discussed is TP53; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.