One of the examples is anassociation (P=3.13×10-27;OR=2504; 95% CI: 126–49 522)between HLA-A*15:02 and the most severe form of carbamazepine-induced hypersensitivitytermed Stevens–Johnson syndrome (SJS) (18).Another example includes an association between HLA-B*57:01 and abacavir-inducedhypersensitivity where it has been demonstrated that the drug is able to bind non-covalentlyto the HLA-B*57:01 protein (12). Here, HLA-B is linked to Schwartz-Jampel syndrome.