The total numbers of tumours between the WT, TgABHD5, TgSRM and TgABHD5+SRM mice did not differ significantly, whereas the numbers of tumours with a volume >3 mm3 markedly increased in the TgABHD5 mice versus the WT group, and additional transgenic expression of SRM in macrophages abolished this effect (Supplementary Fig. 4h). The gene discussed is SRM; the disease is neoplasm.