Prenatal stress enhances glucocorticoid production in the mother and, as a consequence, evokes in the offspring HPA axis hyperactivity, sleep disturbances, reduced neurogenesis in the dentate gyrus of the hippocampus, cognitive deficits, and peripheral insulin resistance (Lemaire et al. 2006; Morley-Fletcher et al. 2004; Szymańska et al. 2009). This evidence concerns the gene INS and Cognitive impairment.