In most animal models (UUO, anti-GBM, ischemia-reperfusion) we recorded down-regulation of 3110045C21Rik during the progress of fibrosis (Fig. 6B) while in the same conditions Cdh1 is down-regulated and Acta2 and Tgfb1 are up-regulated. This evidence concerns the gene ACTA2 and glioblastoma.