Variants at 10 loci attained genome-wide significant evidence of association with T2D (Table 1, Supplementary Figure S4), with the strongest signals mapping to TCF7L2 (lead SNP rs34872471, NC_000010.10:g.114754071T>C, P=6.4 × 10−53) and IGF2BP2 (lead SNP rs11927381, NC_000003.11:g.185508591T>C, P=3.0 × 10−14). The gene discussed is IGF2BP2; the disease is type 2 diabetes mellitus.