APOE and type 2 diabetes mellitus: Common SNPs mapping to the APOE locus have previously been associated with low- and high-density lipoprotein and total cholesterol,22 although the reported lead SNP for these lipids traits (rs4420638, NC_000019.9:g.45422946A>G) is only in moderate LD with that which we report here for T2D susceptibility (EUR r2=0.334 with rs157582).