Notably, although negative or weak SOX7 and AXIN2 staining intensity was seen in over half of all the breast cancers (38/74 SOX7, 43/74 AXIN2; Fig. 4) and β-catenin also exhibited a weak staining intensity in many cases (54/74 β-catenin Fig. 4), most of the specimens with weak β-catenin staining were from patients in TNM I–II. The gene discussed is SOX7; the disease is breast cancer.