Over the past decade, extensive research has been focused on the identification of cellular signaling pathways involved in breast cancer, such as MAPK (Mitogen-activated protein kinases), PI3K/Akt (Phosphatidylinositol-3-kinase/Akt) and Wnt/β-catenin signal pathways7, 8, 9, 10. This evidence concerns the gene AKT1 and breast cancer.