Further examples include the hypoxia inducible factor 3 alpha subunit (Hif3a), whose expression was found to be increased in schizophrenic and bipolar patients [36] or Sgk1 and Tsc22d3, which were associated with high interleukin (IL)-6 levels in patients suffering from the major depressive disorder [37]. The gene discussed is HIF3A; the disease is major depressive disorder.