In addition, eCAT volume was independently associated with presence of CAD (any plaque or luminal narrowing, R2 = 0.11, rpartial = 0.21, p = 0.026), plaque burden (by number of lesions: R2 = 0.22, rpartial = 0.29, p = 0.006) and CAD severity (by maximum lumen narrowing: R2 = 0.22, rpartial = 0.23, p = 0.038) after adjustment for age, diabetes mellitus, hyperlidipemia, BMI, hs-CRP and hs-TnT. The gene discussed is CRP; the disease is coronary artery disorder.