CYP19A1 and breast cancer: Accordingly, and in strict analogy with the study by Kim et al., [92], Jamun fruit extracts have been shown to inhibit over-expressing aromatase and estrogen-dependent MCF-7aro cell proliferation (IC50 27 μg/mL) more effectively as compared to estrogen receptor-negative MDA-MB-231 (IC50 40 μg/mL) breast cancer cells [94].