Consistent with our findings, an interventional experiment using MDA-MB-231 breast cancer cells, which exhibit a high invasive ability in vitro, has demonstrated that IP6 reduces the ability of cancer cells to adhere to collagen IV, FN, and LN and suppresses the capacity of MDA-MB-231 cells to invade and restructure the basement membrane [42]. This evidence concerns the gene FN1 and breast carcinoma.