Moreover, the IC50 values were profoundly lower in mut p53 cancer cells (T47D IC50 = 1.7 μM; MDA231 IC50 = 1.1 μM; ES2 IC50 = 1.9 μM) over wt p53 cancer cells (RKO IC50 = 393.0 μM; HCT116 p53(+/+) IC50 = 128.0 μM) [184]. Here, TP53 is linked to cancer.