While in M13SV1-EGFP-Neo cells and M13MDA435-3 hybrid cells both CpG-ODN and LPS stimulation resulted in IRF7 activation, no nuclear translocation of this transcription factor was detected in MDA-MB-435-Hyg breast cancer cells and M13MDA435-1 hybrid cells (Figure 1B). This evidence concerns the gene IRF7 and breast cancer.