Since both CD8-positive and CD4-positive T cells are engrafted in this model, and both type of T cells infiltrate the EBV-induced DLBCLs, we hypothesized that these T cells might be acting to slow the growth of EBV-induced lymphomas, even if the T cell response to EBV in this model is usually not sufficient to prevent lymphoma growth. This evidence concerns the gene CD8A and lymphoma.