To determine if PD-1/CTLA-4 blockade inhibits EBV-induced lymphoma growth in NSG mice infected with EBV-infected cord blood derived from more than one donor, NSG mice were injected with EBV-infected cord blood derived from two additional donors, and then treated with or without the CTLA-4/PD-1 antibody combination. The gene discussed is PDCD1; the disease is lymphoma.