2004). Initial adhesion and growth of microorganisms on the surface of an implant can be the most critical event in the development of device‐associated infection (Ardehali et al. 2003). The percentage of bacterial cell‐surface attachment is directly proportional to the final mass of biofilm formed. Although apo‐Tf was found to suppress S. epidermidis biofilm production, it has no effect on S. epidermidis initial adhesion. The gene discussed is TF; the disease is infection.