Conversely, the dominant wild-type haplotype (TLR2 ins/ins-IL28B C/C) associated with a better spontaneous resolution of the infection was also found more frequently in both BDs as well as in HCV-related lymphoproliferative disorders compared to CHC, suggesting that, in patients with a lymphoproliferative disease, additional factors may be involved that obstacle the elimination of the virus. Here, IFNL3 is linked to cryohydrocytosis.