Studying combinations of markers, LD blocks and their haplotypes, we suggest that a sub-region with the strongest association to lung cancer susceptibility might locate to the 23.173kb from PPP1R13L intron8 rs1970764 to rs62109563 3′ to CD3EAP. Further fine-mapping studies of cancer susceptibility with other Asian populations should focus on these loci. This evidence concerns the gene PPP1R13L and lung cancer.