High SETD7 expression [hazard ratio (HR), 2.497; 95% CI, 1.632–3.821; P<0.001], tumor size (>5 cm) (HR, 1.605; 95% CI, 1.141–2.258; P = 0.007), and metastasis (HR, 1.722; 95% CI, 1.187–2.496; P = 0.004) are significant independent prognostic factors for poor OS (Table 3). Here, SETD7 is linked to neoplasm.