In a cohort of 324 DCM patients, LMNA c.357-1G>T was detected in one family that consisted of a 64 year-old proband with heart transplantation at age 61, atrial fibrillation, and a pacemaker/ICD and his 33 year-old son diagnosed with heart failure at age 28, premature ventricular contractions (PVCs), and a pacemaker/ICD [31]. The gene discussed is LMNA; the disease is heart failure.