Accordingly, treatment of RAW264.7 cells with the RhCMVgagfliCΔ196-378-infected TeloRF cell lysates did not induce TNF-α (Fig 6B) while treatment of RAW424 cells with the same lysates demonstrated increasing TNF-α induction over time, with peak expression levels occurring with the lysates collected at 48 hours post-infection (Fig 6C). This evidence concerns the gene TNF and infection.