7 Leal Leal EC EC Manivannan Manivannan A A Hosoya Hosoya K K Terasaki Terasaki T T Cunha-Vaz Cunha-Vaz J J Ambrosio Ambrosio AF AF Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy Invest Ophthalmol Vis Sci Invest Ophthalmol Vis Sci 2007 2007 48 48 11 11 5257 5257 5265 5265 doi:10.1167/iovs.07-0112 doi:10.1167/iovs.07-0112 17962481 17962481. The gene discussed is NOS2; the disease is diabetic retinopathy.