Since deregulated c-Myc expression is common in the highly proliferative leukemias and lymphomas which are blocked at an earlier stage of differentiation [20–22], the alteration of c-Myc expression in HL-60 cells was examined by intracytoplasmic staining using flow cytometry after treatment with 1 μM ATRA and 100 nM VD3, each alone or in combination with 300 nM dasatinib for 72 h. This evidence concerns the gene MYC and lymphoma.