As shown in Table 5, BMI, HOMA-IR, AUCglucose and AUCinsulin in PCOS women with a high ZAG level were significantly lower than in PCOS women with a low ZAG level, whereas the M-value, ADI and SHBG were significantly higher in the former (P < 0.05 or P < 0.01). This evidence concerns the gene SHBG and polycystic ovary syndrome.