However, in a recent study of our own group, TOX was also expressed by the neoplastic T-cells in the cases of MF and other CTCL with CD4−CD8+ or CD4−CD8− phenotypes and by (intra-epidermal) CD8+ T-cells in the cases of atopic dermatitis [11]. Here, TOX is linked to primary cutaneous T-cell non-Hodgkin lymphoma.