Those are EWS-ERG t(21;22)(q22;q12), EWS-ETV1 t(7;22)(p22;q12), EWS-E1AF t(17;22)(q12;q12), and EWSFEV t(2;22)(q33;q12) according to their frequency, respectively.8, 9 The detection of ESWR1-FLI1 rearrangement is not diagnostic for ES, also in rhabdomyosarcoma it has been observed.10 This evidence concerns the gene ERG and Ewing sarcoma.