After administration of a CCR4 antagonist, we observed inhibition of SCC-VII tumor growth at day 33 (P < 0.01 for each, Figure 6A) and prolongation of the overall survival time (P < 0.05 for each, Figure 6B) in the CCR4 antagonist-treated group compared to the control groups. The gene discussed is CCR4; the disease is neoplasm.