EPO and Thrombocytopenia: Chronic hypoxia may induce increased erythropoietin production and erythroblastosis, which in turn may result in suppression of platelet production in the bone marrow and ensuing thrombocytopenia.[9] Murray et al have previously demonstrated that SGA neonates have an impaired megakaryocytopoiesis, shown by a marked reduction in circulating megakaryocytes.[26]