Immunohistochemical staining of PDA tissues show that CAFs do not express other somatostatin receptors (not shown), in accordance with the in vitro RT-qPCR results detecting only very small amount of sst2 mRNA (as compared to level observed in the human BON neuroendocrine cell line known to express sst2) [25]. Here, SSTR2 is linked to Patent ductus arteriosus.