CCL2 and neoplasm: Cavtratin can inhibit the vascular leakage induced by carrageenan [51], decrease permeability of tumor microvasculature [52], attenuate heightened permeability of blood–brain barrier induced by monocyte chemoattractant protein-1 [27], and attenuate heightened permeability of mesenteric vessel induced by platelet-activating factor [53].